The course is intended for students that like to get an overview of the state of the art in Molecular Neurobiology. Emphasis is on various tools that are required to get to an in-depth understanding of molecular and cellular processes in neuronal cells. This includes genomics and proteomics, various intervention technologies and measurement systems.
The PhD course includes content of various BSc and MSc courses. It is distinct as it uses selected recent topics in Molecular Neurobiology and includes examples from current research.
This course should NOT be followed by PhD students with a profound knowledge in the Molecular Neuroscience field (see program previous edition).
The course aims at providing knowledge of concepts of Molecular Neurobiology in the context of investigating and understanding gene function in the nervous system.
The following themes were covered in the 2021 edition of the course:
Human genome structure and evolution
Single cell RNAseq, proteomics and cellomics
Viral vectors, gene therapy and CRISPR-CAS
Genetics of complex neurological and psychiatric disorders
REQUIRED BACKGROUND LEVEL
Background knowledge in the neuroscience area is prerequisite. Understanding of cell biology at the level of Alberts, Essential Cell Biology (ISBN 0-8153-3480) is essential.
The course consists mainly of lectures, but also includes interactive elements (e.g. journal clubs, demonstrations)
40 hrs / 1.4 ECTs
Prof. dr. Guus Smit (VU - CNCR) Dr. Frank Jacobs (SILS) Prof. dr. Joost Verhaagen (NIN) Prof. dr. Danielle Posthuma (VU - CNCR)